熬夜使用手機
早上起不來
室內工作
分不清白天黑夜
加班輪班夜班
難調時差
週末補眠睡不飽
週一症候群
小孩晚上不睡覺，早上起不來
過敏長不高
銀髮族晚上睡不著
白天坐著就打瞌睡，頭腦退化不靈光
晚上入眠時間久
翻來覆去，壓力大
依靠安眠藥入睡
但抗藥性越來越強
長期睡不好，容易導致......
掌控好睡眠狀況，避免
解決睡眠問題 調節生理節律
2017 諾貝爾生醫獎得主
發現生物感知晝夜原理
三位美國科學家對生理節律研究的貢獻，讓人們理解生理節律日夜交替以影響睡眠、消化、認知等特定行為。精準光照從此成為精準健康介入的新顯學。
Jeffrey C. Hall
Michael Rosbash
Michael W. Young
This image was originally posted to Flickr by Bengt Nyman at [1] https://flickr.com/photos/97469566@N00/25006072818. [2] https://flickr.com/photos/97469566@N00/38847326642. [3] https://flickr.com/photos/97469566@N00/38162409324. It was reviewed on 6 December 2017 by FlickreviewR 2 and was confirmed to be licensed under the terms of the cc-by-2.0.
生理節律光調節原理
光線進入視網膜光敏細胞，能影響體內褪黑激素的週期分泌，調節「晝夜節律」生理時鐘。
晝夜節律生理時鐘運作機制：
日出而作
日出而作，光照促進穩定情緒的血清素分泌，亦為晚間褪黑激素合成的前導激素
日落而息
日落而息，晚間須減少藍光光害，刺激褪黑激素分泌，啟動睡眠休息機制
睡眠障礙 相關文獻
Ambient bright lighting in the morning improves sleep disturbances of older adults with dementia
Chuen-Ru Liu, Yiing Mei Liou, Jwo-Huei Jou
Sleep Med. 2022 Jan:89:1-9. doi: 10.1016/j.sleep.2021.10.011. Epub 2021 Oct 21.
Light therapy for the treatment of delayed sleep-wake phase disorder in adults: a systematic review
Jefferson Novais Gomes, Cristiane Dias, Renata Silva Brito, Juliana Rodrigues Lopes, Igor Alonso Oliveira, Alexandra Noemi Silva, Cristina Salles
Sleep Sci. 2021 Apr-Jun;14(2):155-163. doi: 10.5935/1984-0063.20200074.
https://pubmed.ncbi.nlm.nih.gov/34381579/
Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults
Timothy M. Brown, George C. Brainard, Christian Cajochen, Charles A. Czeisler, John P. Hanifin, Steven W. Lockley, Robert J. Lucas, Mirjam Münch, John B. O’Hagan, Stuart N. Peirson, Luke L. A. Price, Till Roenneberg, Luc J. M. Schlangen, Kenneth P. Wright Jr
Published: March 17, 2022
https://doi.org/10.1371/journal.pbio.3001571
The effect of light therapy on sleep disorders and psychobehavioral symptoms in patients with Alzheimer’s disease: A meta-analysis
Lili Zang, Xiaotong Liu, Yu Li, Jiang Liu, Qiuying Lu, Yue Zhang, Qinghui Meng
Published: December 6, 2023 https://doi.og/10.1371/journal.pone.0293977
The Effects of Light Therapy on Sleep, Agitation and Depression in People With Dementia: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Kenneth NK Fong, PhD, Xiangyang Ge, and Hilda Cheung, PhD
First published online March 16, 2023 https://doi.org/10.1177/15333175231160682
Light as Therapy for Sleep Disorders and Depression in Older Adults
Philip D. Sloane, MD, MPH, Mariana Figueiro, PhD, and Lauren Cohen, MA
Published in final edited form as: Clin Geriatr. 2008 Mar 1; 16(3): 25–31. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839957/
情緒或憂鬱症 相關文獻
The effect of light therapy on sleep disorders and psychobehavioral symptoms in patients with Alzheimer’s disease: A meta-analysis
Lili Zang, Xiaotong Liu, Yu Li, Jiang Liu, Qiuying Lu, Yue Zhang, Qinghui Meng
Published: December 6, 2023 https://doi.og/10.1371/journal.pone.0293977
The Effects of Light Therapy on Sleep, Agitation and Depression in People With Dementia: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Kenneth NK Fong, PhD, Xiangyang Ge, and Hilda Cheung, PhD
First published online March 16, 2023 https://doi.org/10.1177/15333175231160682
Light as Therapy for Sleep Disorders and Depression in Older Adults
Philip D. Sloane, MD, MPH, Mariana Figueiro, PhD, and Lauren Cohen, MA
Published in final edited form as: Clin Geriatr. 2008 Mar 1; 16(3): 25–31. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839957/
Supplementation of ambient lighting with a task lamp improves daytime alertness and cognitive performance in sleep-restricted individuals
Leilah K Grant, Phoebe C Crosthwaite, Matthew D Mayer, Wei Wang, Robert Stickgold, Melissa A St. Hilaire, Steven W Lockley, Shadab A Rahman
Sleep, Volume 46, Issue 8, August 2023, zsad096, https://doi.org/10.1093/sleep/zsad096
Published: 07 April 2023
失智症 文獻
Ambient bright lighting in the morning improves sleep disturbances of older adults with dementia
Chuen-Ru Liu, Yiing Mei Liou, Jwo-Huei Jou
Sleep Med. 2022 Jan:89:1-9. doi: 10.1016/j.sleep.2021.10.011. Epub 2021 Oct 21.
Pilot Study of the Effects of Bright Ambient Therapy on Dementia Symptoms and Cognitive Function
Chuen-Ru Liu, Yiing Mei Liou, Jwo-Huei Jou
Front Psychol. 2021 Dec 24:12:782160. doi: 10.3389/fpsyg.2021.782160. eCollection 2021.
https://pubmed.ncbi.nlm.nih.gov/35002870/
The Beneficial Role of Photobiomodulation in Neurodegenerative Diseases
by Ayodeji Abijo, Chun-Yuan Lee, Chien-Ying Huang, Pei-Chuan Ho, and Kuen-Jer Tsai
Biomedicines 2023, 11(7),1828;
https://doi.org/10.3390/biomedicines11071828
The effect of light therapy on sleep disorders and psychobehavioral symptoms in patients with Alzheimer’s disease: A meta-analysis
Lili Zang, Xiaotong Liu, Yu Li, Jiang Liu, Qiuying Lu, Yue Zhang, Qinghui Meng
Published: December 6, 2023 https://doi.og/10.1371/journal.pone.0293977
The Effects of Light Therapy on Sleep, Agitation and Depression in People With Dementia: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Kenneth NK Fong, PhD, Xiangyang Ge, and Hilda Cheung, PhD
First published online March 16, 2023 https://doi.org/10.1177/15333175231160682
Supplementation of ambient lighting with a task lamp improves daytime alertness and cognitive performance in sleep-restricted individuals
Leilah K Grant, Phoebe C Crosthwaite, Matthew D Mayer, Wei Wang, Robert Stickgold, Melissa A St. Hilaire, Steven W Lockley, Shadab A Rahman
Sleep, Volume 46, Issue 8, August 2023, zsad096, https://doi.org/10.1093/sleep/zsad096
Published: 07 April 2023
LTMCR 生理節律光調節系統運作
開立醫囑單
醫療專業人員開立醫囑單
系統設定
LTMCR由雲端設定醫囑單參數
設備運作
用戶端節律光灑器依據參數運作
日常使用
用戶照常生活，生活不受影響
調整
醫療專業人員雲端下載使用報告，供後續調整
亮光配方模式
(短時間快速校正生理時鐘)
- 白天運用特殊光譜強光照射，刺激大量血清素分泌。
- 健腦：改善情緒以及認知功能。
- 大幅改善夜間睡眠品質。
模擬日出日落節律配方
(長時間精準微調生理時鐘)
- 精準調節生理時鐘，亦可利用客製化節律模式調整日常作息。
- 白天好心情、好專注；夜間好眠
- 有助自律神經與內分泌協調。
改良為環境用燈
☹︎ 傳統光療燈要直視，活動受限 ☹︎
☺︎ 舒活適系統，可照常生活 ☺︎
應用產品
醫療院所合作專業型
L10 節律光灑器 (高立式)
生活作息加強型
L1 節律深睡燈 (桌上式)
※無亮光配方模式
中華民國發明專利證號：
燈光控制系統 M602327、M603245
具有生理調光的照明裝置及其調光方法 I700961、I737444
符合WELL Building國際標準規範
立燈EML值: 日間>250; 晚間<50，符合WELL Building國際標準規範
EML: Equivalent Melanopic Lux 等效黑視素照度
符合CIE S_026健康照明規範
光源CAF值: 日間>0.92; 夜間<0.28，符合並遠優於CIE S 026健康照明規範
CAF: Circadian Action Factor 晝夜節律生理刺激值
國際IEC認證免除藍光危害
RG0 豁免級，完全無藍光危害
護眼且有效刺激生理節律的光譜特性
Circadian Action Factor(CAF): 中文稱為「生理刺激值」或「晝夜節律因子」或「晝夜節律作用因子」，是學界提出用來評估光源與燈具晝夜節律刺激能力的品質參數。
RG0藍光危害: 豁免級，燈在標準所定義的極限條件下也不造成任何危害。所包含的藍光危害部分定義為在10000s內不造成對視網膜危害。
舒活適－特殊光譜
舒活適特製光譜
1. 加強460~470nm的藍綠光, 提高CAF刺激值，且比一般420~460nm藍光LED不刺眼/護眼
2. 加強540~560nm的綠黃光, 增強明視覺光照度
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L10 節律光灑器 (高立式)
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- 失眠認知行為治療
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- 台灣心理健康發展協會理事長
- 台灣睡眠醫學學會大眾教育委員會主席
- 台灣睡眠醫學學會理事
- 人氣粉絲專頁『睡眠管理職人』發起者
- 台灣睡眠醫學學會合格睡眠檢查技師(第90號)
- 台灣睡眠醫學學會督導級失眠認知行為治療專業人員(台睡心字第6號)
- Podcast『睡眠先生的活力學』主持人
L10節律光灑器 租賃方式
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